Resorcinol → Urolithin B

HRID 1053710Notes

Reaction equation

C1(C=CC=C(O)C=1)O.BrC1C=CC=CC=1C(O)=O.[CH:19]1[C:24](O)=[CH:23][C:22]2[C:26]([O:28][C:29]3[CH:34]=[C:33]([OH:35])[CH:32]=[CH:31][C:30]=3[C:21]=2[CH:20]=1)=[O:27]>>[CH:19]1[CH:20]=[C:21]2[C:30]3[CH:31]=[CH:32][C:33]([OH:35])=[CH:34][C:29]=3[O:28][C:26](=[O:27])[C:22]2=[CH:23][CH:24]=1

Participants

Reactant 3

HCID 5054Resorcinol

HCID 69402-Bromobenzoic acid

HCID 5488186Urolithin A

Product 1

HCID 5380406Urolithin BYield 61.6%

Procedure

Urolithin B was prepared in one step by coupling resorcinol and 2-bromobenzoic acid following the procedure for the preparation of Urolithin A. The pure compound was obtained as a off-white powder with a yield of 61.6%.

Workup

customThe pure compound was obtained as a off-white powder with a yield of 61.6%

Sources & evidence

ORD record: ord-ee41f0d9aac8426c8bfa4624a691f718
Source dataset: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09394269B2

Reaction notes

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