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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1053773Generated: October 25, 2026

3,4-Diethoxyphenylacetic acid → (S)-tert-butyl (4-(5-(3,4-diethoxybenzyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)(2-(dimethylamino)-2-oxoethyl)carbamate

https://huagongshe.com/reaction/1053773

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Diethoxyphenylacetic acidHCID 579813—
ReactantHCID 178484623HCID 178484623—
Product(S)-tert-butyl (4-(5-(3,4-diethoxybenzyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)(2-(dimethylamino)-2-oxoethyl)carbamateHCID 67197972—

Reaction Steps

(S)-tert-butyl (4-(5-(3,4-diethoxybenzyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)(2-(dimethylamino)-2-oxoethyl)carbamate INT-64 was prepared using General Procedure 2, analogously to INT-63, from (S)-tert-butyl (2-(dimethylamino)-2-oxoethyl)(4-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl)carbamate INT-62 and 2-(3,4-diethoxyphenyl)acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09394264B2
Source datasetuspto-grants-2016_07
ORD IDord-2731adfbe435485694836b40fd8a6a1f
Source noteuspto-grants-2016_07