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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1054228Generated: October 26, 2026

Ethyl 2-(hydroxyamino)benzoate → Ethyl 2-(((2-(trifluoromethyl)thiazol-4-yl)methoxy)amino)benzoate

https://huagongshe.com/reaction/1054228

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(hydroxyamino)benzoateHCID 13571167—
Reactant4-(Bromomethyl)-2-(trifluoromethyl)thiazoleHCID 69441347—
ProductEthyl 2-(((2-(trifluoromethyl)thiazol-4-yl)methoxy)amino)benzoateHCID 9025857152%

Reaction Steps

The titled compound was prepared using similar procedure as that of Example-1 (step-2) using ethyl 2-(hydroxyamino)benzoate and product of step 3 described above in 52% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09394300B2
Source datasetuspto-grants-2016_07
ORD IDord-3c9f90db63f14355ab673b252a23c5b1
Source noteuspto-grants-2016_07