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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1054996Generated: November 2, 2026

HCID 72705474, compound → HCID 178427934, compound

https://huagongshe.com/reaction/1054996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 72705474HCID 72705474—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 178427934HCID 178427934100%

Reaction Steps

6,8-Dichloro-2-(2-(1-(4-methoxybenzyl)-5-(pyrrolidin-1-yl)-1H-1,2,4-triazol-3-yl)ethyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyridine (17 mg, 35.0 μmol, Eq: 1.00) in trifluoroacetic acid (539 μl) was heated 3 h under reflux. The product (12.8 mg, 100%) was obtained as a white solid by preparative HPLC. MS: m/z=366.2 (M+H+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09394311B2
Source datasetuspto-grants-2016_07
ORD IDord-f7c5a5f830d444e5b5ed5d99e9f36f4e
Source noteuspto-grants-2016_07