Dimethylamine → HCID 13719288, compound

HRID 1055201Notes

Reaction equation

HRID 1055201 reaction equation
C[O:2][C:3](=O)[CH2:4][C:5](=[O:9])[CH:6]([CH3:8])[CH3:7].C(O)C.[CH3:14][NH:15][CH3:16]>>[CH3:14][N:15]([CH3:16])[C:3](=[O:2])[CH2:4][C:5](=[O:9])[CH:6]([CH3:8])[CH3:7]

Participants

4

Reactant 3

HCID 674DimethylamineHCID 702EthanolHCID 2759969Methyl 4-methyl-3-oxopentanoate

Product 1

HCID 13719288HCID 13719288, compound

Procedure

0.69 mol (100 g) of 4-methyl-3-oxovaleric acid methyl ester and 309 ml 33% dimethylamine in ethanol (about 1.73 mol dimethylamine) were stirred in a pressure reactor for 2 hours at 110° C. After cooling, the solvents were distilled on a rotary evaporator. After drying, 93 g of the title compound were obtained.

Workup

  1. temperatureAfter cooling
  2. distillationthe solvents were distilled on a rotary evaporator
  3. customAfter drying

Sources & evidence

ORD record
ord-ed7d0995b96c418d9762d4ff3c0ee294
Source dataset
uspto-grants-2016_07
Patent number
US09394324B2

Reaction notes

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