2-(Methylamino)ethanol → HCID 86682310, compound

Participants

Reaction Steps

0.351 mol (50 ml) of 4-methyl-3-oxovaleric acid methyl ester and 0.369 mol (29.5 ml) 2-(methylamino)ethanol were stirred for 15 h at 120° C. in a Dean-Stark apparatus. 12 ml of methanol were collected. Subsequently, the excess starting materials 2 h were distilled off on a rotary evaporator (80° C. water bath, 1 mbar). There were obtained 64 g of the title compound.

Provenance & Evidence