Dimethylamine → HCID 53467784, compound

Participants

Reaction Steps

0.337 mol (50 ml) of ethyl 2-oxocyclopentanecarboxylate and 152 ml 33% dimethylamine solution in ethanol were stirred in a pressure reactor for 4 h at 110° C. The reaction mixture was then evaporated to dryness and the crude product was purified over 400 g silica gel with ethyl acetate/hexane 1/1. 17.7 g of the title compound were obtained.

Provenance & Evidence