3-(2-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-benzoic acid → N-(3-{6-[1-(4-Methoxybenzyl)-1H-pyrazol-4-yl]-1H-imidazo[1,2-b]pyrazol-1-yl}-4-methyl-phenyl)-3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide

Participants

Reaction Steps

60 mg (0.12 mmol) of the compound of Example 8A and 31.6 mg (0.12 mmol) of 3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzoic acid [lit.: WO 2004/005281-A1, Example 91b] were reacted and worked up analogously to the procedure of Example 48A. This gave 61 mg (77% of theory) of the title compound.

Provenance & Evidence