HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Methylpiperazin-1-yl)-5-(pentafluoro-lambda6-sulphanyl)benzoic acid trifluoroacetate → N-(3-{6-[1-(4-Methoxybenzyl)-1H-pyrazol-4-yl]-3-methyl-1H-imidazo[1,2-b]pyrazol-1-yl}-4-methylphenyl)-3-(4-methylpiperazin-1-yl)-5-(pentafluoro-lambda6-sulphanyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Methylpiperazin-1-yl)-5-(pentafluoro-lambda6-sulphanyl)benzoic acid trifluoroacetate | HCID 89699560 | — |
| Reactant | 3-{6-[1-(4-Methoxybenzyl)-1H-pyrazol-4-yl]-3-methyl-1H-imidazo[1,2-b]pyrazol-1-yl}-4-methylaniline | HCID 89699861 | — |
| Product | N-(3-{6-[1-(4-Methoxybenzyl)-1H-pyrazol-4-yl]-3-methyl-1H-imidazo[1,2-b]pyrazol-1-yl}-4-methylphenyl)-3-(4-methylpiperazin-1-yl)-5-(pentafluoro-lambda6-sulphanyl)benzamide | HCID 89699504 | — |
Reaction Steps
70 mg (0.17 mmol) of the compound of Example 9A and 78 mg (0.17 mmol) of the compound of Example 17A were reacted and worked up analogously to the procedure of Example 48A. This gave 125 mg (95% of theory) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09394309B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-f7b7093cbb9b46f4bc8e89567ca48434 |
| Source note | uspto-grants-2016_07 |