HCID 10516606, compound → HCID 89699857, compound

HRID 1055679Notes

Reaction equation

HRID 1055679 reaction equation
[CH2:1]([O:3][CH:4]([O:18][CH2:19][CH3:20])[CH2:5][N:6]1[C:10]([NH2:11])=[CH:9][C:8]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[N:7]1)[CH3:2].Br[C:22]1[CH:27]=[C:26]([N+:28]([O-:30])=[O:29])[CH:25]=[C:24]([CH3:31])[C:23]=1[CH3:32]>>[CH2:1]([O:3][CH:4]([O:18][CH2:19][CH3:20])[CH2:5][N:6]1[C:10]([NH:11][C:22]2[CH:27]=[C:26]([N+:28]([O-:30])=[O:29])[CH:25]=[C:24]([CH3:31])[C:23]=2[CH3:32])=[CH:9][C:8]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[N:7]1)[CH3:2]

Participants

3

Reactant 2

HCID 10516606HCID 10516606, compoundHCID 206804421-Bromo-2,3-dimethyl-5-nitrobenzene

Product 1

HCID 89699857HCID 89699857, compound

Procedure

Analogously to Example 13A/Step 1, two batches of 100 mg (0.36 mmol) and of 1.50 g (5.43 mmol), respectively, of the compound of Example 4A and 92 mg (0.40 mmol) and 1.37 g (5.97 mmol), respectively, of 1-bromo-2,3-dimethyl-5-nitrobenzene gave a total of 1.31 g (23% of theory) of the title compound.

Sources & evidence

ORD record
ord-73bf6f977b2e47358c847cdc1d702859
Source dataset
uspto-grants-2016_07
Patent number
US09394309B2

Reaction notes

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