3-Cyano-5-(pentafluoro-lambda6-sulphanyl)benzoic acid → 3-Cyano-N-(3-{6-[1-(4-methoxybenzyl)-1H-pyrazol-4-yl]-1H-imidazo[1,2-b]pyrazol-1-yl}-4-methylphenyl)-5-(pentafluoro-lambda6-sulphanyl)benzamide

Participants

Reaction Steps

80 mg (0.16 mmol) of the compound of Example 60A and 66 mg (0.24 mmol) of the compound of Example 23A were reacted with one another analogously to Example 48A. In deviation from the work-up described therein, here, the mixture was separated directly into its components by preparative HPLC (Method 21). The product-containing fractions were concentrated under reduced pressure and the residue was dried under high vacuum. This gave 84 mg (64% of theory, 80% pure) of the title compound.

Provenance & Evidence