HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-tert-Butyl-5-(pyrrolidin-1-ylmethyl)benzoic acid trifluoroacetate → 3-tert-Butyl-N-{4-methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl}-5-(pyrrolidin-1-ylmethyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-tert-Butyl-5-(pyrrolidin-1-ylmethyl)benzoic acid trifluoroacetate | HCID 89699809 | — |
| Reactant | 4-Methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]aniline | HCID 89700023 | — |
| Product | 3-tert-Butyl-N-{4-methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl}-5-(pyrrolidin-1-ylmethyl)benzamide | HCID 89699759 | — |
Reaction Steps
35 mg (0.12 mmol) of the compound of Example 6A and 47 mg (0.12 mmol) of the compound of Example 22A were reacted and worked up analogously to the procedure of Example 16. This gave 55 mg (95% pure, 81% of theory) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09394309B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-f938a31b79ff49c0b537506c507a0489 |
| Source note | uspto-grants-2016_07 |