Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1055742Generated: November 2, 2026

3-Cyano-5-(pentafluoro-lambda6-sulphanyl)benzoic acid → 3-Cyano-N-{2-fluoro-4-methyl-5-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl}-5-(pentafluoro-lambda6-sulphanyl)benzamide

https://huagongshe.com/reaction/1055742

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Cyano-5-(pentafluoro-lambda6-sulphanyl)benzoic acidHCID 89699812—
Reactant2-Fluoro-4-methyl-5-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]anilineHCID 89700032—
Product3-Cyano-N-{2-fluoro-4-methyl-5-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl}-5-(pentafluoro-lambda6-sulphanyl)benzamideHCID 89700090—

Reaction Steps

55 mg (0.18 mmol) of the compound of Example 12A and 58 mg (85% pure, 0.18 mmol) of the compound of Example 23A were reacted and worked up analogously to the procedure of Example 38. This gave 43 mg (42% of theory) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09394309B2
Source datasetuspto-grants-2016_07
ORD IDord-9b2c1f259afd4b599ab8f3adef7669c8
Source noteuspto-grants-2016_07