3-Cyano-5-(pentafluoro-lambda6-sulphanyl)benzoic acid → 3-Cyano-N-{2-fluoro-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl}-5-(pentafluoro-lambda6-sulphanyl)benzamide

Participants

Reaction Steps

Analogously to the process described in Example 96, 100 mg (0.341 mmol) of the compound of Example 70A and 110 mg (0.341 mmol, 85% pure) of the compound from Example 23A gave 52 mg (28% of theory) of the title compound. Here, purification was by preparative HPLC according to Method 33, and final trituration of the product could be dispensed with.

Provenance & Evidence