HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(6-Fluoro-2-methyl-3-((1-methylcyclopropyl)amino)quinoxalin-5-yl)ethanone → 2-Bromo-1-(6-fluoro-2-methyl-3-((1-methylcyclopropyl)amino)quinoxalin-5-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(6-Fluoro-2-methyl-3-((1-methylcyclopropyl)amino)quinoxalin-5-yl)ethanone | HCID 89781874 | — |
| Reactant | 2-Bromo-1-(3-(tert-butylamino)-6-fluoro-2-methylquinoxalin-5-yl)ethanone | HCID 89781926 | — |
| Product | 2-Bromo-1-(6-fluoro-2-methyl-3-((1-methylcyclopropyl)amino)quinoxalin-5-yl)ethanone | HCID 89782136 | 56% |
Reaction Steps
2-Bromo-1-(6-fluoro-2-methyl-3-((1-methylcyclopropyl)amino)quinoxalin-5-yl)ethanone (610) (846 mg, 56% yield) as a light yellow solid was prepared according to the procedure described for Intermediate 605, using 1-(6-fluoro-2-methyl-3-((1-methylcyclopropyl)amino)quinoxalin-5-yl)ethanone (610b) (1.18 g, 4.31 mmol) as the starting material. m/z (ESI, +ve ion) 352.1/354.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09394297B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-3c6b873cd9c447bf8367d6aca606b726 |
| Source note | uspto-grants-2016_07 |