huagongshe.com
HRID1056383

反应详情

EQUATION

反应方程式

HRID 1056383 的结构方程式

REACTANTS

反应物

3
结构：CC1(N)CCC1.Cl
HCID18332449

1-Methylcyclobutan-1-amine--hydrogen chloride (1/1)

C5H12ClN

结构：O=c1c2ccc(F)c(Br)c2nc(Cl)n1C1CC1
HCID89781975

未命名化合物

结构：CC1(Nc2nc3c(Br)c(F)ccc3c(=O)n2C2CC2)CC1
HCID89782331

未命名化合物

PRODUCTS

生成物

1
结构：CC1(Nc2nc3c(Br)c(F)ccc3c(=O)n2C2CC2)CCC1
HCID89781922

未命名化合物

PROCEDURE

实验过程

8-Bromo-3-cyclopropyl-7-fluoro-2-((1-methylcyclobutyl)amino)quinazolin-4(3H)-one (498a) was prepared according to the procedures described for Intermediate 495a, using 8-bromo-2-chloro-3-cyclopropyl-7-fluoroquinazolin-4(3H)-one (721) and 1-methylcyclobutanamine hydrochloride (Oakwood Chemical) as the starting materials. MS (ESI, pos. ion) m/z: 366.0/368.0 (M+1).