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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1056562Generated: November 2, 2026

Hydrochloric Acid → HCID 89980281, compound

https://huagongshe.com/reaction/1056562

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 131736432HCID 131736432—
SolventEthyl AcetateHCID 8857—
ProductHCID 89980281HCID 89980281223.8%

Reaction Steps

A mixture of (S)-tert-butyl (1-(N-(3-(5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propylsulfonamido)-3-methyl-1-oxobutan-2-yl)carbamate (50 mg, 0.07 mmol) and a saturated solution of HCl in EtOAc (2 mL) was stirred at rt for 2 h. The mixture was concentrated in vacuo to afford the title compound as a white solid (49 mg, 99%). The title compound was characterized by LC-MS as shown below:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09399639B2
Source datasetuspto-grants-2016_07
ORD IDord-bd61aafcf9a147cc823c14e5e2decd5b
Source noteuspto-grants-2016_07