Triethylsilane → HCID 118566580, compound

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Reaction Steps

The title compound was synthesized according to the procedure described in example 126 using 6-chloro-2-cyclohex-1-enyl-quinoline-5-carboxylic acid (4,4-difluoro-cyclohexyl methyl)-amide, palladium on carbon and triethylsilane. 1H NMR (400 MHz, DMSO-d6): δ ppm 8.78-8.80 (m, 1H), 7.96-7.95 (m, 1H), 7.76 (d, J=9.04 Hz, 1H), 7.59 (d, J=8.80 Hz, 1H), 3.25-3.40 (m, 2H), 2.85-2.95 (m, 1H), 2.01-2.15 (m, 2H), 1.86-1.99 (m, 10H), 1.55-1.60 (m, 2H), 1.40-1.45 (m, 2H), 1.23-1.26 (m, 3H). m/z: 421 [M+H]+

Provenance & Evidence