4-Chlorophenol → 4-[2-(4-Chlorophenoxy)-4-(methylamino)-3-nitrophenyl]-6-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one

Participants

Role	Name	HCID	Charge
Reactant	4-Chlorophenol	HCID 4684	—
Reactant	4-[2-Fluoro-4-(methylamino)-3-nitrophenyl]-6-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one	HCID 123586401	—
Product	4-[2-(4-Chlorophenoxy)-4-(methylamino)-3-nitrophenyl]-6-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one	HCID 123910815	—

Reaction Steps

This compound was synthesized according to the procedure of Example 1, Step 1, using 4-[2-fluoro-4-(methylamino)-3-nitrophenyl]-6-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one and p-chlorophenol as the starting materials. LCMS calculated for C27H32ClN4O5Si (M+H)+: m/z=555.2. found: 555.1.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09399640B2
Source dataset	uspto-grants-2016_07
ORD ID	ord-02eefd63dd084aea99264eccab6c0f96
Source note	uspto-grants-2016_07