HRID1056998

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4684

4-Chlorophenol

C6H5ClO

结构：CNc1ccc(-c2cn(C)c(=O)c3c2ccn3COCC[Si](C)(C)C)c(F)c1[N+](=O)[O-]

HCID123586401

未命名化合物

PRODUCTS

生成物

结构：CNc1ccc(-c2cn(C)c(=O)c3c2ccn3COCC[Si](C)(C)C)c(Oc2ccc(Cl)cc2)c1[N+](=O)[O-]

HCID123910815

未命名化合物

PROCEDURE

实验过程

This compound was synthesized according to the procedure of Example 1, Step 1, using 4-[2-fluoro-4-(methylamino)-3-nitrophenyl]-6-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one and p-chlorophenol as the starting materials. LCMS calculated for C27H32ClN4O5Si (M+H)+: m/z=555.2. found: 555.1.

WORKUP

后处理

customThis compound was synthesized

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-02eefd63dd084aea99264eccab6c0f96
来源数据集: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09399640B2
来源说明: uspto-grants-2016_07

反应 SMILES

F[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[C:6]([NH:11][CH3:12])[CH:5]=[CH:4][C:3]=1[C:13]1[C:14]2[CH:23]=[CH:22][N:21]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:31])([CH3:30])[CH3:29])[C:15]=2[C:16](=[O:20])[N:17]([CH3:19])[CH:18]=1.[Cl:32][C:33]1[CH:38]=[CH:37][C:36]([OH:39])=[CH:35][CH:34]=1>>[Cl:32][C:33]1[CH:38]=[CH:37][C:36]([O:39][C:2]2[C:7]([N+:8]([O-:10])=[O:9])=[C:6]([NH:11][CH3:12])[CH:5]=[CH:4][C:3]=2[C:13]2[C:14]3[CH:23]=[CH:22][N:21]([CH2:24][O:25][CH2:26][CH2:27][Si:28]([CH3:31])([CH3:30])[CH3:29])[C:15]=3[C:16](=[O:20])[N:17]([CH3:19])[CH:18]=2)=[CH:35][CH:34]=1