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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1057146Generated: October 26, 2026

1-Butynyltrimethylsilane → 3-(But-1-yn-1-yl)-7-methoxybenzofuran

https://huagongshe.com/reaction/1057146

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-ButynyltrimethylsilaneHCID 43926—
Reactant7-Methoxybenzofuran-3-yl trifluoromethanesulfonateHCID 20827133—
Product3-(But-1-yn-1-yl)-7-methoxybenzofuranHCID 66806652—

Reaction Steps

The title compound was prepared from 7-methoxybenzofuran-3-yl trifluoromethanesulfonate and Intermediate 39 following General Procedure B. 1H NMR (DMSO-d6, 400 MHz): δ 8.24 (s, 1H), 7.26 (t, 1H), 7.17 (d, 1H), 6.99 (d, 1H), 3.94 (s, 3H), 2.52-2.47 (m, 2H), 1.21 (t, 3H). LCMS: 201 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09399646B2
Source datasetuspto-grants-2016_07
ORD IDord-07b85c30b506421bbd80528d956653af
Source noteuspto-grants-2016_07