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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1057211Generated: October 27, 2026

Iodobenzene → (E)-5-(1-(4-Bromophenyl)-2-phenylbut-1-en-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole

https://huagongshe.com/reaction/1057211

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodobenzeneHCID 11575—
Reactant(4-Bromophenyl)boronic acidHCID 79599—
Reactant5-(But-1-yn-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazoleHCID 66793270—
Product(E)-5-(1-(4-Bromophenyl)-2-phenylbut-1-en-1-yl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazoleHCID 66802799—

Reaction Steps

The title compound was prepared from Intermediate 3, iodobenzene, and (4-bromophenyl)boronic acid following General Procedure C. LCMS: 403 [(M-THP+H)+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09399646B2
Source datasetuspto-grants-2016_07
ORD IDord-fc7e6c27686a4555b810bdb3fa449b38
Source noteuspto-grants-2016_07