HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-2-azido-1-benzylethylamine → (2R)-3-Phenylpropane-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-2-azido-1-benzylethylamine | HCID 14802497 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (2R)-3-Phenylpropane-1,2-diamine | HCID 12699299 | — |
Reaction Steps
A sample of the compound from step 4 (1.2 g, 6.8 mmol) is hydrogenated (4 atm) in ethanol over 1.2 g of 10% Pd/C for 21.5 hours at room temperature. The mixture is filtered to remove the catalyst, and the solvent is removed to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06514944B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-0469f3e95c63410db270f6aafc3f1542 |
| Source note | uspto-grants-2003_02 |