4-Toluenesulfonyl chloride → 6-[2-(Toluene-4-sulfonyloxy)-ethyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester

HRID 105739Notes

Reaction equation

HRID 105739 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([CH2:18][CH2:19][OH:20])[cH:14][c:15]2[CH2:16][CH2:17]1.[CH3:21][c:22]1[cH:23][cH:24][c:25]([S:28](=[O:29])(=[O:30])[Cl:31])[cH:26][cH:27]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([CH2:18][CH2:19][O:20][S:28]([c:25]3[cH:24][cH:23][c:22]([CH3:21])[cH:27][cH:26]3)(=[O:29])=[O:30])[cH:14][c:15]2[CH2:16][CH2:17]1

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 67006783tert-butyl 6-(2-hydroxyethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate

Product 1

HCID 580427946-[2-(Toluene-4-sulfonyloxy)-ethyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-4634314bfca041538f720cf865de819c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…