Diethylene Glycol Monoethyl Ether → Carbazole-4-carboxamide

HRID 1057414ノート

反応式

HRID 1057414 の反応式
[CH2:1]1[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]([C:14]([NH2:16])=[O:15])[CH2:3][CH2:2]1.CCOCCOCCO>[Pd]>[CH:1]1[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[C:4]([C:14]([NH2:16])=[O:15])=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 8146Diethylene Glycol Monoethyl EtherHCID 227387261,2,3,4-Tetrahydrocarbazole-4-carboxamide

生成物 1

HCID 22741084Carbazole-4-carboxamide

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

A 1,2,3,4-tetrahydrocarbazole-4-carboxamide or 4-carboxhydrazide (13) is dehydrogenated by refluxing in a solvent such as carbitol in the presence of Pd/C to produce the carbazole-4-carboxamide. Alternately, treatment of (13) with DDQ in an appropriate solvent such as dioxane yields carbozole (14).

出典と根拠

ORDレコード
ord-dacd84b38b7d449fb0949083205d69c1
出典データセット
uspto-grants-2003_02
特許番号
US06514984B1

反応ノート

読み込み中…