HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Dimethoxymethyl)-1,8-naphthyridine → 7-(Dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Dimethoxymethyl)-1,8-naphthyridine | HCID 17750175 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 7-(Dimethoxymethyl)-1,2,3,4-tetrahydro-1,8-naphthyridine | HCID 17750176 | — |
Reaction Steps
Dimethoxypyridino[3,2-e]pyridin-2-ylmethane was dissolved in methanol (0.5M) followed by addition of 10% Pd/C), and subjected to hydrogenation at ballon pressure. The mixture was filtered through celite and concentrated by rotary evaporation. EI-MS m/z 209 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06514964B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-46fec5666b514783adf423d7fff154e8 |
| Source note | uspto-grants-2003_02 |