HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 18672149, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 5-Chloro-1,2-oxazole-3-carboxylic acid | HCID 22311430 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 18672149 | HCID 18672149 | — |
Reaction Steps
To solution of 5-chloroisoxazole-3-carboxylic acid (Example 22, 0.253 g, 1.71 mmol, 2.0 equiv) in CHCl3 (21 mL) was added SOCl2 (9 mL). The reaction mixture was heated to reflux for 26 h. The volatiles were removed under reduced pressure to give crude 5-chloroisoxazole-3-carbonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06514997B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-8d79b400620d4a2685d983a02a345fb4 |
| Source note | uspto-grants-2003_02 |