HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 22734450, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Hydrate;hydrochloride | HCID 21885828 | — |
| Reactant | HCID 22734091 | HCID 22734091 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 22734450 | HCID 22734450 | 80% |
Reaction Steps
Compound 185 (0.19 g) obtained in Example 185 was suspended in ethanol (1 ml), mixed with a 24% aqueous sodium hydroxide solution (1.3 ml), and heat-refluxed for 2 hours. The resultant was allowed to stand for cooling, mixed with water, and adjusted to PH 2 by adding 2N hydrochloric acid water. The precipitated solid was collected by filtration to give Compound 186 (0.14 g, 80%) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06514996B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-fc46b7094fd949a4ae681c5c2cc8f36c |
| Source note | uspto-grants-2003_02 |