HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclobutylamine → HCID 22734150, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclobutylamine | HCID 75645 | — |
| Reactant | 7-Methoxy-1-benzofuran-2-carboxylic acid | HCID 606037 | — |
| Product | HCID 22734150 | HCID 22734150 | — |
Reaction Steps
Substantially the same procedure as in Example 219 was repeated using a starting material, 7-methoxybenzofuran-2-carboxylic acid, and cyclobutylamine to give N-Cyclobutyl-7-methoxybenzofuran-2-carboxamide (Compound 289a). Successively, it was formylated to give N-cyclobutyl-4-formyl-7-methoxybenzofuran-2-carboxamide (Compound 289b), then compound 289b was reacted with methylamine hydrochloride to give Compound 289 as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06514996B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-2e5a0367c4c749c4946133972af8f12b |
| Source note | uspto-grants-2003_02 |