Water → 158397-38-7

Temperature

60 °C

To a solution of 2,3-dichlorobenzaldehyde (0.314 mmol) in acetonitrile (1 ml) was added solid trimethylsulfonium iodide (0.314 mmol, 64 mg), potassium hydroxide (0.628 mmol, 35 mg), and water (0.079 mmol, 1.4 μl). The heterogeneous mixture were heated in a capped test tube at 60° C. for 3 h. The suspension was then diluted with ethyl acetate (1 ml) and washed with saturated sodium bicarbonate (1×1 ml) and water (3×0.5 ml). The tube was concentrated by vacuum centrifuge over 1 hour and the resulting 2,3-dichlorophenyloxirane used without further purification

1. washwashed with saturated sodium bicarbonate (1×1 ml) and water (3×0.5 ml)
2. concentrationThe tube was concentrated by vacuum centrifuge over 1 hour
3. customthe resulting 2,3-dichlorophenyloxirane used without further purification

ORD record

ord-fc7ec124ce32463b96aa639cf9001865

Source dataset

uspto-grants-2003_02

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US06515023B2