4-Hydroxybenzoic Acid → 4-(4-Nitrophenoxy)benzoic acid

HRID 1058583Notes

Reaction equation

HRID 1058583 reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.Cl[C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][CH:13]=1.C[O-].[Na+]>CS(C)=O>[N+:18]([C:15]1[CH:16]=[CH:17][C:12]([O:1][C:2]2[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=2)=[CH:13][CH:14]=1)([O-:20])=[O:19]

Participants

5

Reactant 3

HCID 1354-Hydroxybenzoic AcidHCID 74741-Chloro-4-nitrobenzeneHCID 10942334Sodium Methoxide

Product 1

HCID 2920664-(4-Nitrophenoxy)benzoic acid

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Following the general procedure of J. Polym. Sci., Polym. Chem. Ed. (1980), 18(10). 3069-80, 4-hydroxybenzoic acid, 1-chloro-4-nitro-benzene and sodium methoxide were heated in DMSO at 130° C. to afford the title compound.

Sources & evidence

ORD record
ord-d39d05f58de444a19e2cc9dd4e03cf35
Source dataset
uspto-grants-2003_02
Patent number
US06518267B1

Reaction notes

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