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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1058583Generated: October 31, 2026

4-Hydroxybenzoic Acid → 4-(4-Nitrophenoxy)benzoic acid

https://huagongshe.com/reaction/1058583

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxybenzoic AcidHCID 135—
Reactant1-Chloro-4-nitrobenzeneHCID 7474—
ReactantSodium MethoxideHCID 10942334—
SolventDimethyl SulfoxideHCID 679—
Product4-(4-Nitrophenoxy)benzoic acidHCID 292066—

Reaction Steps

Following the general procedure of J. Polym. Sci., Polym. Chem. Ed. (1980), 18(10). 3069-80, 4-hydroxybenzoic acid, 1-chloro-4-nitro-benzene and sodium methoxide were heated in DMSO at 130° C. to afford the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06518267B1
Source datasetuspto-grants-2003_02
ORD IDord-d39d05f58de444a19e2cc9dd4e03cf35
Source noteuspto-grants-2003_02