化工社化工社 化学情報印刷レポート · 研究参考用
Acetone → HCID 178527052、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | Phenylacetaldehyde | HCID 998 | — |
| 反応物 | HCID 178509653 | HCID 178509653 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178527052 | HCID 178527052 | 62.9% |
反応手順
A solution of 21 g (84.3 mmol) of α-phenylbenzenemethanamine phosphinate in 60 ml of anhydrous ethanol is brought to reflux. 20.25 g (168.5 mmol) of phenylacetaldehyde in 20 ml of anhydrous ethanol are added dropwise. An abundant white precipitate forms. After addition, refluxing is continued for 2.5 hours. After cooling, 100 ml of acetone are added. The precipitate obtained is filtered off and washed with the same solvent. 18.6 g of product are recovered (yield=62.9%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06518260B1 |
| 出典データセット | uspto-grants-2003_02 |
| ORD ID | ord-8ceae928c87544b1b2cced9b986ce7c7 |
| 出典メモ | uspto-grants-2003_02 |