反应详情

A solution of 21 g (84.3 mmol) of α-phenylbenzenemethanamine phosphinate in 60 ml of anhydrous ethanol is brought to reflux. 20.25 g (168.5 mmol) of phenylacetaldehyde in 20 ml of anhydrous ethanol are added dropwise. An abundant white precipitate forms. After addition, refluxing is continued for 2.5 hours. After cooling, 100 ml of acetone are added. The precipitate obtained is filtered off and washed with the same solvent. 18.6 g of product are recovered (yield=62.9%).

1. temperatureto reflux
2. additionAfter addition
3. temperaturerefluxing
4. temperatureAfter cooling
5. customThe precipitate obtained
6. filtrationis filtered off
7. washwashed with the same solvent
8. custom18.6 g of product are recovered (yield=62.9%)