Ethyl 2-(4-bromobenzyl)acrylate → Ethyl 3-(4-bromophenyl)-2-[[hydroxy[2-phenyl-1-[[(phenyl-methoxy)carbonyl]amino]ethyl]phosphinyl]methyl]propanoate

Participants

Reaction Steps

The process is performed according to the operating conditions described in 1.6., starting with 2 g (6.27 mmol) of [2-phenyl-1-[(phenylmethoxy)carbonyl]aminoethyl]phosphinic acid synthesized in 1.4. and 2 g (7.44 mol) of ethyl 4-bromo-α-methylenebenzenepropanoate. 3.1 g of product are recovered (yield=84.1%)

Provenance & Evidence