Benzyl chloroformate → HCID 178465414, compound

HRID 1058769Notes

Reaction equation

[NH2:1][CH:2]([PH:4](=[O:6])[OH:5])[CH3:3].Cl[C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9]>>[C:12]1([CH2:11][O:10][C:8]([NH:1][CH:2]([PH:4](=[O:5])[OH:6])[CH3:3])=[O:9])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 2

HCID 10387Benzyl chloroformate

HCID 3018298Aminoethylphosphinic acid

Product 1

HCID 178465414HCID 178465414, compound

Procedure

The process is performed according to the operating conditions described in 1.4., starting with 1.7 g (15.6 mmol) of (1-aminoethyl)phosphinic acid and 3.12 g (18.29 mmol) of benzyl chloroformate. 2.8 g of product are recovered (yeld=73.9%).

Workup

custom2.8 g of product are recovered (yeld=73.9%)

Sources & evidence

ORD record: ord-d591f6ba6a6c43e6a4e593f2c2df6e51
Source dataset: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06518260B1

Reaction notes

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