Benzyl chloroformate → HCID 178522840, compound

HRID 1058773Notes

Reaction equation

HRID 1058773 reaction equation
[NH2:1][CH:2]([PH:9](=[O:11])[OH:10])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.Cl[C:13]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:14]>>[C:17]1([CH2:16][O:15][C:13]([NH:1][CH:2]([PH:9](=[O:10])[OH:11])[C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=2)=[O:14])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 10387Benzyl chloroformateHCID 178509673HCID 178509673, compound

Product 1

HCID 178522840HCID 178522840, compoundYield 90%

Procedure

The process is performed according to the operating conditions described in 1.4., starting with 1 g (5.85 mmol) of (aminophenylmethyl)phosphinic acid and 1.17 g (6.86 mmol) of benzyl chloroformate. 1.6 g of product are recovered (yield=90%).

Workup

  1. custom1.6 g of product are recovered (yield=90%)

Sources & evidence

ORD record
ord-5085cb329d244f14a5a544d349e662ec
Source dataset
uspto-grants-2003_02
Patent number
US06518260B1

Reaction notes

Loading…