Chlorodiphenylmethane → N-diphenylmethyloxy-tert-butyl-(dimethyl-tert-butylamino-carbonyl-methyl)-amine

HRID 1059043Notes

Reaction equation

[C:1]([N:5]([C:7]([CH3:16])([CH3:15])[C:8]([NH:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[OH:6])([CH3:4])([CH3:3])[CH3:2].[C:17]1([CH:23](Cl)[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:17]1([CH:23]([C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)[O:6][N:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[C:7]([CH3:16])([CH3:15])[C:8]([NH:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

Reactant 2

HCID 7035Chlorodiphenylmethane

HCID 22182216Tert-butyl-(dimethyl-tert-butylaminocarbonyl-methyl)-hydroxylamine

Product 1

HCID 23563824N-diphenylmethyloxy-tert-butyl-(dimethyl-tert-butylamino-carbonyl-methyl)-amineYield 62.7%

Procedure

The compound is prepared in analogy to example A13 from tert-butyl-(dimethyl-tert-butylaminocarbonyl-methyl)-hydroxylamine and diphenylmethylchloride in 62.7% yield as colorless crystals, m.p. 89-92° C.

Sources & evidence

ORD record: ord-aa7e93e6e37a4adf855a5a869c799e30
Source dataset: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06518326B1

Reaction notes

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