2-amino-N-cyclohexylacetamide → HCID 178514400, compound

HRID 1059130Notes

Reaction equation

HRID 1059130 reaction equation
[NH2:1][CH2:2][C:3]([NH:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:4].Cl.[NH2:13][N:14]=[CH:15]N1C=CC=N1>O1CCOCC1>[NH2:13][N:14]=[CH:15][NH:1][CH2:2][C:3]([NH:5][CH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:4]

Participants

4

Reactant 2

HCID 4085922-amino-N-cyclohexylacetamideHCID 690661591-Aminoiminomehtylpyrazole hydrochloride

Product 1

HCID 178514400HCID 178514400, compoundYield 84%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A round-bottomed flask is charged with 15 g of 2-amino-N-(cyclohexyl)-acetamide, 14,6 g 1-aminoiminomehtylpyrazole hydrochloride and 100 ml of dioxane. After 18 h stirring at reflux, the reaction medium is cooled to room temperature and precipitate which has formed is filtered off with suction. 16 g of a white solid are obtained.

Workup

  1. temperatureat reflux
  2. customprecipitate which has formed
  3. filtrationis filtered off with suction

Sources & evidence

ORD record
ord-c752f4e9d50c47168940e60c8974c0b0
Source dataset
uspto-grants-2003_02
Patent number
US06518458B1

Reaction notes

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