反应详情

Under an argon atmosphere, p-dibromobenzene (9.99 g), 4-methoxyphenylboronic acid (2.03 g) and tetrakistriphenylphosphine palladium (497 mg) were dissolved in dimethoxyethane (20 ml). A 2M aqueous sodium carbonate solution (20 ml) was added and the mixture was heated under reflux for 14 h. The reaction mixture was cooled to room temperature and the precipitated crystals were collected by filtration. The obtained crystals were dissolved in ethyl acetate and insoluble materials were filtered off. The solvent was evaporated and the obtained solid was washed with hexane to give the title compound (2.09 g) as a colorless solid.

1. temperaturethe mixture was heated
2. temperatureunder reflux for 14 h
3. filtrationthe precipitated crystals were collected by filtration
4. dissolutionThe obtained crystals were dissolved in ethyl acetate
5. filtrationinsoluble materials were filtered off
6. customThe solvent was evaporated
7. washthe obtained solid was washed with hexane