HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylphenyl boronic acid → 2-methyl-1-(2'-methyl[1,1'-biphenyl]-3-yl)-1-(1-trityl-1H-imidazol-4-yl)-1-propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylphenyl boronic acid | HCID 2733267 | — |
| Reactant | 1-(3-bromophenyl)-(1-trityl-1H-imidazol-4-yl)-2-methyl-1-propanol | HCID 18668522 | — |
| Product | 2-methyl-1-(2'-methyl[1,1'-biphenyl]-3-yl)-1-(1-trityl-1H-imidazol-4-yl)-1-propanol | HCID 18668588 | 59.2% |
Reaction Steps
By the reaction in the same manner as in Example 1-(i) using o-tolylboronic acid (0.69 g) and 1-(3-bromophenyl)-2-methyl-1-(1-trityl-1H-imidazol-4-yl)-1-propanol (1.01 g), the amorphous title compound (0.61 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518257B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-66a90cf4a11f4014b6aa0b1ce44b56ab |
| Source note | uspto-grants-2003_02 |