HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridinium chloride → 1-(1H-imidazol-4-yl)-2-methyl-1-[3-(2-thienyl)phenyl]-1-propanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | HCID 18668565 | HCID 18668565 | — |
| Product | 1-(1H-imidazol-4-yl)-2-methyl-1-[3-(2-thienyl)phenyl]-1-propanol | HCID 178450135 | 87.6% |
Reaction Steps
By the reaction in the same manner as in Example 4-(iii) using 2-methyl-1-[3-(2-thienyl)phenyl]-1-(1-trityl-1H-imidazol-4-yl)-1-propanol (1.21 g) and pyridine hydrochloride (465 mg), the title compound (585 mg) was obtained as colorless plate crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518257B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-beca95f8ccd24fb5961d6d87d87c2ce9 |
| Source note | uspto-grants-2003_02 |