Hydrochloric Acid → HCID 178418905, compound
Reaction equation
[ClH:1].[OH:2][C:3]1[C:12]2[C:7](=[C:8]([NH:13][C@H:14]3[CH2:19][CH2:18][C@H:17]([NH:20]C(OC(C)(C)C)=O)[CH2:16][CH2:15]3)[CH:9]=[CH:10][CH:11]=2)[C:6]([CH3:28])=[CH:5][N:4]=1>>[ClH:1].[OH:2][C:3]1[C:12]2[C:7](=[C:8]([NH:13][C@H:14]3[CH2:15][CH2:16][C@H:17]([NH2:20])[CH2:18][CH2:19]3)[CH:9]=[CH:10][CH:11]=2)[C:6]([CH3:28])=[CH:5][N:4]=1Participants
3
Procedure
According to the method of Step A of this example, deprotection with concentrated hydrochloric acid was performed by using Intermediate 140 to obtain the title compound.
Sources & evidence
- ORD record
- ord-5c825aac16db4c78bc62bbf1ee6b3093
- Source dataset
- uspto-grants-2006_08
- Patent number
- US07094789B2
Reaction notes
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