HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridinium chloride → N-(6-{4-[1-hydroxy-1-(1H-imidazol-4-yl)-2-methylpropyl]phenyl}-2-pyridyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridinium chloride | HCID 10176127 | — |
| Reactant | N-(6-(4-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]phenyl}-2-pyridyl)acetamide | HCID 18668520 | — |
| Product | N-(6-{4-[1-hydroxy-1-(1H-imidazol-4-yl)-2-methylpropyl]phenyl}-2-pyridyl)acetamide | HCID 178474125 | 59.4% |
Reaction Steps
By the reaction in the same manner as in Example 4-(iii) using N-(6-(4-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]phenyl}-2-pyridyl)acetamide (1.48 g) and pyridine hydrochloride (520 mg), the title compound (520 mg) was obtained as colorless powder crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518257B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-f02e2ba5a4eb4f86a312bedca4d1fa87 |
| Source note | uspto-grants-2003_02 |