Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfamide | HCID 82267 | — |
| Reactant | 1-Benzyl-4-piperidylamine | HCID 415852 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | HCID 11000095 | HCID 11000095 | 105.7% |
Reaction Steps
To a solution of 3.0 g of 4-amino-1-benzylpiperidine in dimethoxyethane (20 ml) was added 1.35 g of sulfamide. The resulting mixture was stirred at 100° C. for 10 minutes and then reacted at 130° C. for 1 hour. After distilling off the solvent under reduced pressure, 4.0 g of the title compound was obtained as a brown oily substance.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06518423B1 |
|---|
| Source dataset | uspto-grants-2003_02 |
|---|
| ORD ID | ord-2dd291900b634825b4c1f7ee5072c464 |
|---|
| Source note | uspto-grants-2003_02 |
|---|
