2-(4-Bromophenyl)-4,4-dimethyl-4,5-dihydrooxazole → N,N-Dimethyl-2-[[4-(4,4-dimethyl-2-oxazolin-2-yl)phenyl]hydroxymethyl]imidazole-1-sulfonamide

Participants

Role	Name	HCID	Charge
Reactant	2-(4-Bromophenyl)-4,4-dimethyl-4,5-dihydrooxazole	HCID 403395	—
Reactant	2-formyl-N,N-dimethyl-1H-imidazole-1-sulfonamide	HCID 10262290	—
Product	N,N-Dimethyl-2-[[4-(4,4-dimethyl-2-oxazolin-2-yl)phenyl]hydroxymethyl]imidazole-1-sulfonamide	HCID 18670283	40.3%

Reaction Steps

Similar to Production Example 164, 4.54 g of N,N-dimethyl-2-formylimidazole-1-sulfonamide was treated with 7.0 g of 2-(4-bromophenyl)-4,4-dimethyl-2-oxazoline to thereby give 3.41 g of the title compound.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06518423B1
Source dataset	uspto-grants-2003_02
ORD ID	ord-ae3128d34ff3454195302e08aea84a3f
Source note	uspto-grants-2003_02