Tetrabutylammonium Fluoride → HCID 86592279, compound

Participants

Reaction Steps

8-(6-Iodopurin-9-ylmethyl)-10-methoxymethyl-10H-pyrazino[2,3-b][1,4]benzothiazine was treated by the same method as the one of Example 9 to thereby give 8-(6-iodopurin-9-ylmethyl)-10H-pyrazino[2,3-b][1,4]benzothiazine. Next, this product was treated with bis(tert-butyldimethylsiloxymethyl)-2-propyn-1-ol by the same method as the one of Example 1417. The compound thus obtained was further treated with tetrabutylammonium fluoride in accordance with the method of Example 1386-3 to thereby give the title compound.

Provenance & Evidence