HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (10H-Pyrazino[2,3-b][1,4]benzothiazin-8-yl)acetamidine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (10H-Pyrazino[2,3-b][1,4]benzothiazin-8-yl)acetamidine | HCID 18670382 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (10H-Pyrazino[2,3-b][1,4]benzothiazin-8-yl)acetamidine hydrochloride | HCID 18670381 | — |
Reaction Steps
(10H-Pyrazino[2,3-b][1,4]benzothiazin-8-yl) acetamidine was dissolved in a small amount of methanol and a solution of hydrogen chloride in ethyl acetate was added thereto under ultrasonication. Thus, the title compound was obtained almost quantitatively as the precipitated orange crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518423B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-6ad375a7622c44c28a0864f6c5081fde |
| Source note | uspto-grants-2003_02 |