Hydrochloric Acid → HCID 23437555, compound

HRID 1059481Notes

Reaction equation

HRID 1059481 reaction equation
[CH2:1]([S:13]([C:16]1[CH:25]=[CH:24][C:19]([C:20]([O:22]C)=[O:21])=[CH:18][CH:17]=1)(=[O:15])=[O:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[OH-].[K+].Cl>CO.O>[CH2:1]([S:13]([C:16]1[CH:25]=[CH:24][C:19]([C:20]([OH:22])=[O:21])=[CH:18][CH:17]=1)(=[O:15])=[O:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 18629906HCID 18629906, compound

Product 1

HCID 23437555HCID 23437555, compoundYield 66.7%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Conditions

Temperature
55 °C

Procedure

Methyl 4-dodecylsulfonylbenzoate (5), (approximately 63.43 mMole) was suspended in methanol (100 mL), and 85%-potassium hydroxide (10.5 g, 64.67 mMole) in water (20 mL) added. The mixture was heated to 50-60° C. for 15 minutes during which time the solid went into solution. The solution was then cooled and added to ice cold 2N-HCl (1 L). The white solid was filtered off, washed with water, then methanol and finally air-dried to give 15.0 g of 4-dodecylsulfonylbenzoic acid.

Workup

  1. temperatureThe solution was then cooled
  2. filtrationThe white solid was filtered off
  3. washwashed with water
  4. dry with materialmethanol and finally air-dried

Sources & evidence

ORD record
ord-3f37e088a8cb4c5d8b3449fc186e332b
Source dataset
uspto-grants-2003_02
Patent number
US06521395B1

Reaction notes

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