HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1059688Generated: November 1, 2026
Phenethylamine → 6-(1-Chloroethyl)-5-iodo-4-(2-phenylethylamino)pyrimidine
https://huagongshe.com/reaction/1059688
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Phenethylamine | HCID 1001 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Chloro-6-(1-chloroethyl)-5-iodopyrimidine | HCID 15452299 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 6-(1-Chloroethyl)-5-iodo-4-(2-phenylethylamino)pyrimidine | HCID 15452300 | — |
Reaction Steps
In 20 ml of toluene were dissolved 2-phenylethylamine (0.6 g) and triethylamine (0.6 g), then, 4-chloro-6-(1-chloro-ethyl)-5-iodopyrimidine (1.5 g) was added to the solution, and the mixture was heated at about 60° C. for 3 hours while stirring.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06521627B1 |
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| Source dataset | uspto-grants-2003_02 |
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| ORD ID | ord-edd44ce9681c4d66bf25a094f3cb537b |
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| Source note | uspto-grants-2003_02 |
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